Dr. Cheng-Chia (Fred) Wu, MD, PhD is a board-certified radiation oncologist with a focus on pediatric malignancies and central nervous system tumors.  He is a tenure-track Assistant Professor in the Department of Radiation Oncology at Columbia University Irving Medical Center, and is currently the executive lead of the Initiative for Drug Delivery Innovation (IDDI) in Childhood Brain Tumors at Columbia.  The IDDI program has opened clinical trials utilizing both focused ultrasound and convection enhanced delivery for children with diffuse intrinsic pontine glioma (DIPG)/diffuse mudline glioma (DMG). He led a clinical trial using focused ultrasound to open the blood brain barrier to deliver a histone deacetylase inhibitor for patients with progressive DIPG/DMG, and is currently planning additional clinical studies using this technology.  He also runs the IDDI preclinical laboratory dedicated to identifying novel drug combinations and treatment strategies for focused ultrasound to fight childhood brain tumors. He serves on the pediatric scientific advisory board for the Focused Ultrasound Foundation and his goal is to help bridge the gap between technology and patient care to advance drug delivery for children with brain tumors.